Two cases of Stevens-Johnson syndrome following intake of klavox with review of literature

Eur Arch Otorhinolaryngol. 2009 Aug;266(8):1327-30. doi: 10.1007/s00405-008-0785-7. Epub 2008 Aug 13.

Abstract

We present two case reports of Stevens-Johnson syndrome (triad of fever, stomatitis and conjunctivitis) due to klavox (amoxicillin + clavulanic acid) which has been reported in few publications as etiology but it is not commonly seen. We conclude that klavox can precipitate development of SJS.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amoxicillin / adverse effects*
  • Anti-Bacterial Agents / adverse effects
  • Biopsy
  • Clavulanic Acid / adverse effects*
  • Diagnosis, Differential
  • Drug Combinations
  • Follow-Up Studies
  • Humans
  • Male
  • Mouth Mucosa / pathology
  • Pharyngitis / drug therapy
  • Stevens-Johnson Syndrome / chemically induced*
  • Stevens-Johnson Syndrome / diagnosis

Substances

  • Anti-Bacterial Agents
  • Drug Combinations
  • Clavulanic Acid
  • Amoxicillin