Efficacy of Canadian folic acid food fortification

Food Nutr Bull. 2008 Jun;29(2 Suppl):S225-30. doi: 10.1177/15648265080292S127.

Abstract

Canada mandated that cereal grains, especially white flour, be fortified with folic acid by mid-1998. Between 0.1 and 0.2 mg of additional synthetic folic acid per day has been provided through this initiative. The current paper describes how this took place, and the epidemiological effects that occurred in the Canadian population, including higher blood folate levels and a decline in the prevalence of neural tube defects.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Canada
  • Edible Grain*
  • Female
  • Flour
  • Folic Acid / administration & dosage*
  • Folic Acid / adverse effects
  • Folic Acid / blood*
  • Folic Acid Deficiency / blood
  • Folic Acid Deficiency / epidemiology
  • Folic Acid Deficiency / prevention & control*
  • Food, Fortified*
  • Humans
  • Male
  • Middle Aged
  • Neural Tube Defects / blood
  • Neural Tube Defects / epidemiology
  • Neural Tube Defects / prevention & control*
  • Nutritional Status
  • Preconception Care

Substances

  • Folic Acid