How safe is hand-assisted laparoscopic donor nephrectomy?--results of 200 live donor nephrectomies by two different techniques

Nephrol Dial Transplant. 2009 Jan;24(1):293-7. doi: 10.1093/ndt/gfn463. Epub 2008 Aug 18.

Abstract

Background: Despite the rapid introduction of laparoscopic living donor nephrectomy, doubts exist about safety compared with open surgery. Early series have often reported on selective donor groups. We present a consecutive, prospective analysis of morbidity following hand-assisted laparoscopic donor nephrectomy (HALDN) compared with historical controls undergoing open donation (ODN) in a total of 200 living donors at a single UK centre.

Methods: The results of 144 consecutively performed HALDN donors were compared to 56 preceding ODN patients. Patients with multiple arteries, right-sided nephrectomies and obesity were included. Data on recovery and complications were collected prospectively and consecutively.

Results: There were two (1.4%) major complications in the HALDN group and one in the ODN group (1.8%, P = 0.629). Additionally, there were 24 minor complications in 23 HADLN patients (16.7%), compared with 21 in 21 ODN patients (37.5%, P = 0.003). Time taken to return to normal activity and mean post-operative stay was significantly shorter for the HALDN group. There was no mortality in either group.

Conclusions: Contrary to concerns, we report a safe experience with HALDN with a low rate of major complications. Furthermore, our patients spend less time in hospital with an earlier return to normal activity compared with open donation.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Female
  • Humans
  • Kidney Failure, Chronic / surgery
  • Kidney Transplantation*
  • Laparoscopy / adverse effects*
  • Laparoscopy / methods*
  • Living Donors*
  • Male
  • Middle Aged
  • Nephrectomy / adverse effects*
  • Nephrectomy / methods*
  • Postoperative Complications / etiology
  • Prospective Studies
  • Tissue and Organ Harvesting / adverse effects*
  • Tissue and Organ Harvesting / methods*