Increased serum pigment epithelium derived factor levels in Type 2 diabetes patients

Diabetes Res Clin Pract. 2008 Oct;82(1):e5-7. doi: 10.1016/j.diabres.2008.06.019. Epub 2008 Aug 19.

Abstract

Serum PEDF levels (mean (S.D.)) were increased in 96 Type 2 diabetic vs. 54 non-diabetic subjects; 5.3 (2.8) vs. 3.2 (2.0)mug/ml, p<0.001. In diabetes, PEDF correlated with BMI, serum creatinine and LDL-cholesterol, but not with other lipids, HbA1c or CRP. PEDF did not differ by drugs, complications, or gender.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Body Mass Index
  • C-Reactive Protein / metabolism
  • Cholesterol, LDL / blood
  • Creatinine / metabolism
  • Diabetes Mellitus, Type 2 / blood*
  • Eye Proteins / blood*
  • Female
  • Glycated Hemoglobin A / metabolism
  • Humans
  • Lipids / blood
  • Male
  • Middle Aged
  • Nerve Growth Factors / blood*
  • Serpins / blood*

Substances

  • Cholesterol, LDL
  • Eye Proteins
  • Glycated Hemoglobin A
  • Lipids
  • Nerve Growth Factors
  • Serpins
  • pigment epithelium-derived factor
  • C-Reactive Protein
  • Creatinine