Severe, Permanent Orbital Disease in Herpes Zoster Ophthalmicus

Orbit. 2008;27(4):325-7. doi: 10.1080/01676830802222852.

Abstract

A 63-year-old man with HZO presented with involvement of cranial nerves II, III, IV, V, and VI, with proptosis, raised intraocular pressure, and chemosis. With the aid of orbital imaging, a diagnosis of orbital apex inflammation secondary to HZO was confirmed, and he was treated with intravenous acyclovir and oral steroids. Despite this, he made a minimal recovery at eight months following presentation. Severe, irreversible orbital disease may develop following HZO, and an ischemic vasculitis may play a role in the pathogenesis of the disease.

Publication types

  • Case Reports

MeSH terms

  • Acyclovir / therapeutic use
  • Antiviral Agents / therapeutic use
  • Blepharoptosis / diagnosis
  • Blepharoptosis / drug therapy
  • Blepharoptosis / etiology
  • Conjunctival Diseases / diagnosis
  • Conjunctival Diseases / drug therapy
  • Conjunctival Diseases / etiology
  • Drug Therapy, Combination
  • Edema / diagnosis
  • Edema / drug therapy
  • Edema / etiology
  • Exophthalmos / diagnosis
  • Exophthalmos / drug therapy
  • Exophthalmos / etiology
  • Glucocorticoids / therapeutic use
  • Herpes Zoster Ophthalmicus / complications*
  • Herpes Zoster Ophthalmicus / diagnosis
  • Herpes Zoster Ophthalmicus / drug therapy
  • Humans
  • Infusions, Intravenous
  • Intraocular Pressure
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Ocular Hypertension / diagnosis
  • Ocular Hypertension / drug therapy
  • Ocular Hypertension / etiology
  • Orbital Diseases / diagnostic imaging
  • Orbital Diseases / drug therapy
  • Orbital Diseases / etiology*
  • Prednisolone / therapeutic use
  • Tomography, X-Ray Computed

Substances

  • Antiviral Agents
  • Glucocorticoids
  • Prednisolone
  • Acyclovir