Recurrence of cardiorespiratory events following repeat DTaP-based combined immunization in very low birth weight premature infants

Aline Flatz-Jequier; Klara M Posfay-Barbe; Riccardo E Pfister; Claire-Anne Siegrist

doi:10.1016/j.jpeds.2008.03.043

Recurrence of cardiorespiratory events following repeat DTaP-based combined immunization in very low birth weight premature infants

J Pediatr. 2008 Sep;153(3):429-31. doi: 10.1016/j.jpeds.2008.03.043.

Authors

Aline Flatz-Jequier¹, Klara M Posfay-Barbe, Riccardo E Pfister, Claire-Anne Siegrist

Affiliation

¹ Department of Pediatrics, Children's Hospital, University Hospitals of Geneva and Medical Faculty of the University of Geneva, Geneva, Switzerland.

PMID: 18718262
DOI: 10.1016/j.jpeds.2008.03.043

Abstract

We evaluated the tolerance to immunization of 64 very low birth weight preterm infants. Thirty-three of the infants experienced a cardiorespiratory event after the first vaccination, and 6 of these 33 (18%) had a recurrence after the second vaccination, including 2 infants previously discharged to home. A cardiorespiratory event associated with the first vaccination was the sole risk factor for recurrence identified.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Apnea / chemically induced
Apnea / epidemiology*
Bradycardia / chemically induced*
Bradycardia / epidemiology
Diphtheria-Tetanus-acellular Pertussis Vaccines / administration & dosage
Diphtheria-Tetanus-acellular Pertussis Vaccines / adverse effects*
Humans
Immunization / methods*
Incidence
Infant
Infant, Newborn
Infant, Premature*
Infant, Very Low Birth Weight*
Prognosis
Recurrence
Retrospective Studies
Risk Factors
Switzerland / epidemiology

Substances

Diphtheria-Tetanus-acellular Pertussis Vaccines