Coronary artery aneurysm and thrombosis following chronic ephedra use

Int J Cardiol. 2010 Feb 18;139(1):e11-3. doi: 10.1016/j.ijcard.2008.06.081. Epub 2008 Aug 20.

Abstract

Ephedra, also known as Ma Huang, was commonly used to enhance athletic performance, "fat burning", and weight loss before its removal from the United States in April 2004 due to acute adverse health reactions including lethal arrhythmias, stroke, vasoconstriction, and myocardial infarction. We report the case of a 29-year-old patient with acute myocardial infarction, secondary to coronary artery aneurysms and thrombosis who reported use of Ma Huang, Xenadrine(r)RFA, and Hydroxycut at recommended dosages for a combined total of approximately 2 years. Other causes of coronary artery aneurysm and hypercoagulability were ruled out. Our case exemplifies the long-term (as opposed to acute) danger of ephedrine products and the first case of coronary artery aneurysm associated with its use.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Chest Pain / chemically induced*
  • Coronary Aneurysm / chemically induced*
  • Coronary Aneurysm / diagnostic imaging
  • Coronary Thrombosis / chemically induced*
  • Coronary Thrombosis / diagnostic imaging
  • Ephedra sinica / adverse effects*
  • Humans
  • Male
  • Plant Preparations / adverse effects*
  • Radiography
  • Ultrasonography

Substances

  • Plant Preparations