TB, HIV-associated TB and multidrug-resistant TB on Thailand's border with Myanmar, 2006-2007

Trop Med Int Health. 2008 Oct;13(10):1288-96. doi: 10.1111/j.1365-3156.2008.02139.x. Epub 2008 Aug 20.


Objective: To measure the burden and improve management of tuberculosis (TB), HIV-associated TB and MDR TB in Tak Province, Thailand, which borders Myanmar.

Methods: From September 2006 to August 2007, we collected uniform data about TB cases and enhanced human immunodeficiency virus (HIV) counselling and testing. We provided mycobacterial culture and drug-susceptibility testing in public or non-governmental organization facilities. Patients were classified by nationality and, for non-Thais, by migration status.

Results: Of 1662 TB cases in the 12-month period, 1087 (65%) occurred in non-Thais. Of non-Thais, 415 (38%) lived in Myanmar but crossed the border for healthcare. HIV infection was diagnosed in 18% of Thais compared with 12% of non-Thais (P < 0.01); HIV status was unknown for 22% of Thais and 27% of non-Thais (P = 0.02). Overall, multidrug-resistant (MDR) TB was diagnosed in 27 patients, 19 (70%) in non-Thais. Among TB cases never previously treated for TB, no MDR cases were diagnosed in Thais or in Myanmar refugees, but six cases were diagnosed in migrants from Myanmar.

Conclusions: In Thailand, TB, HIV-associated TB and MDR TB in migrants from Myanmar are important public health problems; they need to be resolved in both the countries.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • AIDS-Related Opportunistic Infections / epidemiology*
  • Adolescent
  • Adult
  • Aged
  • Antitubercular Agents / therapeutic use
  • Emigration and Immigration / statistics & numerical data
  • Female
  • HIV Infections / epidemiology
  • HIV-1*
  • Health Priorities
  • Humans
  • Male
  • Middle Aged
  • Registries
  • Sentinel Surveillance
  • Thailand / epidemiology
  • Tuberculosis, Multidrug-Resistant / epidemiology*
  • Tuberculosis, Pulmonary / drug therapy
  • Tuberculosis, Pulmonary / epidemiology*
  • World Health Organization


  • Antitubercular Agents