Abstract
New multivalent cationic lipids, one of them showing high efficiency and low toxicity in cell transfection, have been obtained by attaching guanidinium groups at the lower rim of calix[4]arenes.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Calixarenes / chemical synthesis
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Calixarenes / chemistry
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Calixarenes / metabolism*
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Calixarenes / toxicity*
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Cell Line, Tumor
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DNA / genetics
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DNA / metabolism
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Electrophoresis
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Guanidine / chemistry*
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Humans
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Phenols / chemical synthesis
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Phenols / chemistry
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Phenols / metabolism*
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Phenols / toxicity*
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Phosphatidylethanolamines / metabolism
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Transfection / instrumentation*
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Transfection / methods*
Substances
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1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine
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Phenols
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Phosphatidylethanolamines
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calix(4)arene
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Calixarenes
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DNA
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Guanidine