Aim: To review the scientific preclinical background and clinical studies of current methods of periodontal regeneration in the treatment of infrabony defects and soft tissue deficiencies.
Method: Five commissioned review papers including two systematic reviews were scrutinized by a group of experts in order to derive consensus conclusions, clinical relevance/implications and to propose future research requirements.
Results: The following five papers were assessed: 1. Biological mediators and periodontal regeneration: a review of enamel matrix proteins at the cellular and molecular levels. 2. Regeneration of periodontal tissues: combination of barrier membranes and grafting materials - Biological foundation and preclinical evidence. 3. Clinical outcomes with bioactive agents alone or in combination with grafting or GTR 4. Treatment of gingival recession with coronally advanced flap procedures. A systematic review. 5. Soft tissue management at implant sites.