Proteomics joins the search for microRNA targets

Cell. 2008 Aug 22;134(4):560-2. doi: 10.1016/j.cell.2008.08.008.


Two recent studies published in Nature (Baek et al. 2008; Selbach et al., 2008) analyze changes in the proteome in response to individual microRNAs (miRNAs). This approach is a powerful means to identify miRNA targets and to quantify the contribution of translational repression to posttranscriptional gene silencing by miRNAs.

MeSH terms

  • Animals
  • Computational Biology
  • HeLa Cells
  • Humans
  • MicroRNAs / genetics*
  • Proteins / metabolism*
  • Proteomics / methods*


  • MicroRNAs
  • Proteins