Evaluation of the antiparasitic effect of aqueous garlic (Allium sativum) extract in hymenolepiasis nana and giardiasis

J Egypt Soc Parasitol. 1991 Aug;21(2):497-502.

Abstract

The effect of serial dilutions of crude garlic (Allium sativum) extract on adult Hymenolepis nana was studied to detect the minimal lethal concentration which was found to be 1/20. A. sativum was tried in the treatment of 10 children infected with H. nana and 26 infected with G. lamblia as 5 ml crude extract in 100 ml water in 2 doses per day, or commercial preparation (0.6 mg capsules) 2 capsules twice/day for 3 days. A sativum was found to be efficient, safe and shortens the duration of treatment. The possible mode of action of A. sativum and the correlation between the clinical and parasitological findings were discussed.

MeSH terms

  • Animals
  • Child
  • Child, Preschool
  • Garlic*
  • Giardia / drug effects
  • Giardiasis / drug therapy*
  • Humans
  • Hymenolepiasis / drug therapy*
  • Hymenolepis / drug effects
  • Plant Extracts / therapeutic use
  • Plants, Medicinal*

Substances

  • Plant Extracts