A complete remission of sclerosing rhabdomyosarcoma with multiple lung and bone metastases treated with multi-agent chemotherapy and peripheral blood stem cell transplantation (PBSCT): a case report

Anticancer Res. 2008 Jul-Aug;28(4C):2361-7.

Abstract

A case of sclerosing rhabdomyosarcoma (RMS) in a young adult with multiple lung and skip bone metastases is reported. Complete remission was achieved with this patient by treatment with multi-agent chemotherapy and peripheral blood stem cell transplantation (PBSCT) based on the pathological diagnosis of RMS using a specimen obtained during an open biopsy at the first consultation. He is still alive and has been continuously disease free for 12 years after surgery. This is a very rare case with successful treatment using PBSCT for a sclerosing RMS that presented with multiple distant metastases at the first consultation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Bone Neoplasms / drug therapy
  • Bone Neoplasms / secondary
  • Bone Neoplasms / therapy*
  • Combined Modality Therapy
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Leg
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / secondary
  • Lung Neoplasms / therapy*
  • Male
  • Rhabdomyosarcoma / drug therapy
  • Rhabdomyosarcoma / pathology
  • Rhabdomyosarcoma / therapy*