Mendelian randomisation and causal inference in observational epidemiology

PLoS Med. 2008 Aug 26;5(8):e177. doi: 10.1371/journal.pmed.0050177.


Nuala Sheehan and colleagues describe how Mendelian randomization provides an alternative way of dealing with the problems of observational studies, especially confounding.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Epidemiology*
  • Humans
  • Observation*
  • Randomized Controlled Trials as Topic*