Use of Active Surveillance Cultures to Detect Asymptomatic Colonization With Carbapenem-Resistant Klebsiella Pneumoniae in Intensive Care Unit Patients

Infect Control Hosp Epidemiol. 2008 Oct;29(10):966-8. doi: 10.1086/590661.

Abstract

Carbapenem-resistant Klebsiella pneumoniae is emerging as a significant healthcare-associated pathogen. Clinical cultures detect only a fraction of the colonized population, and patients with asymptomatic colonization are at risk of invasive infection. Additional study of the impact of detection of asymptomatic colonization on subsequent infection and transmission is needed.

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Carbapenems / pharmacology*
  • Carrier State / epidemiology*
  • Carrier State / microbiology
  • Cross Infection / epidemiology
  • Cross Infection / microbiology
  • Culture Media
  • Humans
  • Intensive Care Units*
  • Klebsiella Infections / epidemiology
  • Klebsiella Infections / microbiology
  • Klebsiella pneumoniae / drug effects
  • Klebsiella pneumoniae / isolation & purification*
  • New York City
  • Population Surveillance / methods*
  • beta-Lactam Resistance*

Substances

  • Anti-Bacterial Agents
  • Carbapenems
  • Culture Media