Myeloneuropathy in a dentist

Clin Toxicol (Phila). 2008 Dec;46(10):1095-6. doi: 10.1080/15563650802356617.


We present a case of a 49-year-old male dentist with myeloneuropathy. He used nitrous oxide frequently in his practice, and denied recreational use. Magnetic resonance imaging (MRI) of his cervical and thoracic spinal cord demonstrated a hyperintense signal on T2 within the posterior columns. The patient was treated with vitamin B12 and l-methionine. A repeat MRI of his cervical spinal cord 3 months after hospital discharge showed complete regression of the hyperintense signal on T2 within the posterior columns.

Publication types

  • Case Reports

MeSH terms

  • Anesthetics, Inhalation / adverse effects*
  • Dentists
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Nitrous Oxide / adverse effects*
  • Occupational Exposure / adverse effects*
  • Spinal Cord Diseases / chemically induced*
  • Spinal Cord Diseases / diagnosis
  • Workplace / standards


  • Anesthetics, Inhalation
  • Nitrous Oxide