Intranasal transmission of hepatitis C virus: virological and clinical evidence

Clin Infect Dis. 2008 Oct 1;47(7):931-4. doi: 10.1086/591699.


Intranasal transmission of hepatitis C virus (HCV) via contaminated drug-sniffing implements is a potential but unconfirmed source of viral infection. We demonstrate the virological plausibility of intranasal transmission by confirming that blood and HCV RNA are present in the nasal secretions and drug-sniffing implements of HCV-infected intranasal drug users recruited from a community health clinic in New York City.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Administration, Intranasal
  • Hepacivirus / genetics
  • Hepatitis C / transmission*
  • Humans
  • Nasal Mucosa / virology
  • Polymerase Chain Reaction
  • Substance-Related Disorders / complications*