Prof. CHEN Quan-xin holds that proper application of reinforcing-reducing manipulation is the key for therapeutic effect of acupuncture. Clinically, he holds that the acupuncturist must carefully observe arrival of qi under the needle. In the present paper, Prof. CHEN's needling manipulation methods are preliminarily summarized, focusing a more systematic exposition on core manipulations of CHEN's needling manipulation, i. e. CHEN's Feizhen manipulation, CHEN's qi-inducing manipulation and CHEN's grading reinforcing-reducing manipulation. The author holds that only careful study, grasping the essentials and techniques of manipulation can attain very good clinical therapeutic effect in clinic.