Effect of bariatric surgery on pregnancy outcome

Int J Gynaecol Obstet. 2008 Dec;103(3):246-51. doi: 10.1016/j.ijgo.2008.07.008. Epub 2008 Sep 2.

Abstract

Objective: To compare the perinatal outcomes of women who delivered before with women who delivered after bariatric surgery.

Methods: A retrospective study was undertaken to compare perinatal outcomes of women who delivered before with women who delivered after bariatric surgery in a tertiary medical center between 1988 and 2006. A multivariate logistic regression model was constructed to control for confounders.

Results: During the study period, 301 deliveries preceded bariatric surgery and 507 followed surgery. A significant reduction in rates of diabetes mellitus (17.3% vs 11.0; P=0.009), hypertensive disorders (23.6% vs 11.2%; P<0.001), and fetal macrosomia (7.6% vs 3.2%; P=0.004) were noted after bariatric surgery. Bariatric surgery was found to be independently associated with a reduction in diabetes mellitus (OR 0.42, 95% CI 0.26-0.67; P<0.001), hypertensive disorders (OR 0.38, 95% CI 0.25-0.59; P<0.001), and fetal macrosomia (OR 0.45, 95% CI 0.21-0.94; P=0.033).

Conclusion: A decrease in maternal complications, such as diabetes mellitus and hypertensive disorders, as well as a decrease in the rate of fetal macrosomia is achieved following bariatric surgery.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Bariatric Surgery / adverse effects*
  • Bariatric Surgery / statistics & numerical data
  • Confidence Intervals
  • Confounding Factors, Epidemiologic
  • Diabetes, Gestational / epidemiology
  • Female
  • Fetal Macrosomia / epidemiology
  • Humans
  • Hypertension / epidemiology
  • Logistic Models
  • Obesity, Morbid / epidemiology
  • Obesity, Morbid / surgery*
  • Odds Ratio
  • Pregnancy
  • Pregnancy Complications / diagnosis
  • Pregnancy Complications / epidemiology*
  • Pregnancy Outcome / epidemiology*
  • Retrospective Studies
  • Risk Factors