Review
doi: 10.1016/0968-0004(91)90055-z.
Is hsp70 the cellular thermometer?
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- PMID: 1877088
- DOI: 10.1016/0968-0004(91)90055-z
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Review
Is hsp70 the cellular thermometer?
Trends Biochem Sci.
1991 Apr.
Abstract
Cells respond to an increase in temperature by inducing the synthesis of the heat shock proteins, which are a small set of evolutionarily conserved proteins. We review the evidence leading us to suggest that the free pool of one of these proteins, hsp70, serves as a cellular thermometer that regulates the expression of all heat shock proteins.
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