[Ofloxacin is contraindicated in case of G6PD deficiency: is it evidenced based?]

Rev Med Interne. 2009 Apr;30(4):355-7. doi: 10.1016/j.revmed.2008.07.007. Epub 2008 Sep 5.
[Article in French]


G6PD deficiency is very frequent with almost 400 millions of patients worldwide in Asia, Africa and Mediterranean. G6PD deficiency is involved in mild or severe haemolysis and the precipitating factor is usually a drug. More than 100 drugs have been implicated and fluoroquinolones are one of the more classic. However, the literature review shows that only a few observations have been clearly documented.

Publication types

  • Case Reports

MeSH terms

  • Contraindications
  • Diabetes Complications / drug therapy
  • Diabetes Complications / microbiology*
  • Escherichia coli Infections / drug therapy*
  • Female
  • Glucosephosphate Dehydrogenase Deficiency / complications*
  • Humans
  • Insulin / therapeutic use
  • Middle Aged
  • Ofloxacin / therapeutic use*
  • Urinary Tract Infections / drug therapy*


  • Insulin
  • Ofloxacin