A new HLA-DR4 allele, DRB1*0474, with an unusual residue at position 77

C Desaules; J Villard; J-M Tiercy

doi:10.1111/j.1399-0039.2008.01129.x

A new HLA-DR4 allele, DRB1*0474, with an unusual residue at position 77

Tissue Antigens. 2008 Nov;72(5):500-1. doi: 10.1111/j.1399-0039.2008.01129.x. Epub 2008 Sep 5.

Authors

C Desaules¹, J Villard, J-M Tiercy

Affiliation

¹ National Reference Laboratory for Histocompatibility, Transplantation Immunology Unit, University Hospital, Geneva, Switzerland.

PMID: 18778325
DOI: 10.1111/j.1399-0039.2008.01129.x

Abstract

We report here a new DR4 allele, DRB1*0474, identified in a volunteer hematopoietic stem cell donor of the Swiss National Registry. DRB1*0474 differs from DRB1*040701 by two nucleotide residues resulting in a single Thr --> Asn substitution at codon 77.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Amino Acid Substitution
Base Sequence
Exons / genetics*
HLA-DR4 Antigen / genetics*
Humans
Molecular Sequence Data
Sequence Alignment

Substances

HLA-DR4 Antigen