Parathyroid hormone and the cardiovascular system

Curr Osteoporos Rep. 2008 Jun;6(2):77-83. doi: 10.1007/s11914-008-0014-8.


The classical actions of parathyroid hormone (PTH) are well recognized, but its effects on other target tissues, such as the cardiovascular system, are less appreciated. Several studies have evaluated the effects of PTH in patients with primary hyperparathyroidism in order to understand potential cardiovascular effects in terms of hypertension, cardiovascular mortality, left ventricular function, and endothelial function. We review these studies and evaluate the cellular mechanisms that may affect these outcomes.

Publication types

  • Review

MeSH terms

  • Animals
  • Cardiovascular Diseases / physiopathology
  • Cardiovascular System / physiopathology*
  • Disease Models, Animal
  • Humans
  • Hyperparathyroidism / physiopathology
  • Hypertension / physiopathology
  • Parathyroid Hormone / physiology*
  • Ventricular Dysfunction, Left / physiopathology


  • Parathyroid Hormone