Psoas abscesses caused by Paracoccidioides brasiliensis in an adolescent

Mycopathologia. 2009 Feb;167(2):89-93. doi: 10.1007/s11046-008-9152-x. Epub 2008 Sep 10.

Abstract

Objective: In order to describe the case of an adolescent who developed psoas abscesses caused by Paracoccidiodes brasiliensis.

Description: A 12-year-old boy was admitted with a history of daily fever and global lymph nodes enlargement. He had been treated in the last 6 years, with irregular use of the drugs, for an acute form of paracoccidioidomycosis (PCM). He presented a tenderness fluctuating polyadenopathy in all cervical, submandibular, supraclavicular, axillary, and inguinal chains; several lymph nodes were up to 4 cm in diameter, hardened and coalescent. After 1 month of unsuccessful therapy with SMX-TMP, the patient presented a pain in the right groin and difficulty to walk. CT scan showed a global retroperitoneal lymph nodes enlargement, some with central necrosis and two bigger collections adjacent to both psoas muscles. A surgical drainage of the collections was performed for several times. The patient received a total of 1.9 g of Amphotericin B. After 1 month of the last surgical procedure, CT scan showed only a residual collection, and the patient was sent to ambulatory follow-up. We hypothesed that the retroperitoneal lymph nodes became a coalescent mass that fistulized to the psoas compartment.

Comments: The patient presented a febrile lymphoproliferative syndrome that is frequently seen in children with PCM. Although a polymorphic manifestation is observed in this disease, psoas abscess is a rare complication of PCM. The health professionals that take care of the patients with PCM must pay attention to the possibility of this one more complication.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Amphotericin B / therapeutic use
  • Antifungal Agents / administration & dosage
  • Antifungal Agents / therapeutic use
  • Child
  • Directly Observed Therapy
  • Fever
  • Humans
  • Infusions, Intravenous
  • Itraconazole / administration & dosage
  • Itraconazole / therapeutic use
  • Lymph Nodes / diagnostic imaging
  • Male
  • Paracoccidioides / isolation & purification
  • Paracoccidioidomycosis / complications*
  • Paracoccidioidomycosis / drug therapy
  • Paracoccidioidomycosis / physiopathology
  • Patient Compliance
  • Psoas Abscess / diagnostic imaging
  • Psoas Abscess / drug therapy
  • Psoas Abscess / etiology*
  • Psoas Abscess / surgery
  • Radiography
  • Trimethoprim, Sulfamethoxazole Drug Combination / administration & dosage
  • Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use

Substances

  • Antifungal Agents
  • Itraconazole
  • Amphotericin B
  • Trimethoprim, Sulfamethoxazole Drug Combination