Major liver resection for hepatocellular carcinoma in the morbidly obese: a proposed strategy to improve outcome

World J Surg Oncol. 2008 Sep 10;6:100. doi: 10.1186/1477-7819-6-100.


Background: Morbid obesity strongly predicts morbidity and mortality in surgical patients. However, obesity's impact on outcome after major liver resection is unknown.

Case presentation: We describe the management of a large hepatocellular carcinoma in a morbidly obese patient (body mass index >50 kg/m2). Additionally, we propose a strategy for reducing postoperative complications and improving outcome after major liver resection.

Conclusion: To our knowledge, this is the first report of major liver resection in a morbidly obese patient with hepatocellular carcinoma. The approach we used could make this operation nearly as safe in obese patients as it is in their normal-weight counterparts.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Carcinoma, Hepatocellular / complications
  • Carcinoma, Hepatocellular / surgery*
  • Female
  • Hepatectomy* / adverse effects
  • Humans
  • Liver Neoplasms / complications
  • Liver Neoplasms / surgery*
  • Obesity, Morbid / complications*
  • Postoperative Complications / etiology
  • Postoperative Complications / prevention & control
  • Treatment Outcome