Inconsistent statistics about the number of HIV/AIDS cases in Iran and misinformation about HIV/AIDS among Iranian adolescents necessitate proper understanding and knowledge of HIV/AIDS transmission and prevention. This is particularly important since many issues related to HIV/AIDS, such as sex, homosexuality, and drug use, are taboo topics in the Islamic world. We analyzed Farsi-language educational and informational small media items to ascertain the nature of HIV/AIDS-related material available in society. While all of the documents mentioned sexual contact as a means of transmitting the virus, and the majority (87%) mentioned condom use as a preventive means, mention of homosexuality (43%) and prostitution (17%) was lacking in most. Thus, mention of "safe sex" strategies was not avoided due to fear of promoting sex outside of marriage, as has been noted in other Islamic nations. Mention of intravenous drug use in 90% of the documents shows an acknowledgment of the drug problem in the nation, and an effort to curb its harmful sequelae. Therefore, while certain issues such as sex, condoms, and drug use were well represented in the documents analyzed, additional inclusion of topics such as homosexuality and prostitution, issues already discussed infrequently in society, can help to better educate the population and curb the spread of this life-threatening disease.