Two-component signaling systems and cell cycle control in Caulobacter crescentus

Adv Exp Med Biol. 2008;631:122-30. doi: 10.1007/978-0-387-78885-2_8.

Abstract

Recent work on the regulation ofprokaryotic growth and development by two-component systems (TCS) has revealed unsuspected levels of complexity. In the dimorphic freshwater bacterium Caulobacter crescentus, TCS provide stringent temporal and spatial control of cellular development and cell-cycle progression. While the environmental signals modulating TCS regulatory networks are largely unknown, the components of the network and their interactions with each other are increasingly well-defined. Here, we present an overview of TCS regulation of cell-cycle control in C. crescentus.

Publication types

  • Review

MeSH terms

  • Bacterial Proteins / genetics
  • Bacterial Proteins / physiology
  • Caulobacter crescentus / cytology*
  • Caulobacter crescentus / genetics
  • Caulobacter crescentus / metabolism*
  • Cell Cycle / physiology*
  • Cell Cycle Proteins / genetics
  • Cell Cycle Proteins / physiology
  • DNA-Binding Proteins / genetics
  • DNA-Binding Proteins / physiology
  • Genes, Bacterial
  • Histidine Kinase
  • Models, Biological
  • Peptide Hydrolases / metabolism
  • Phosphorylation
  • Protein Kinases / metabolism
  • Signal Transduction / physiology*
  • Transcription Factors / genetics
  • Transcription Factors / physiology

Substances

  • Bacterial Proteins
  • Cell Cycle Proteins
  • CtrA protein, Caulobacter
  • DNA-Binding Proteins
  • DnaA protein, Bacteria
  • Transcription Factors
  • Protein Kinases
  • Histidine Kinase
  • Peptide Hydrolases