Vertebral deformities and inflammatory bowel disease

Eur J Gastroenterol Hepatol. 2008 Sep;20(9):819-21. doi: 10.1097/MEG.0b013e3282f8889f.


Loss of bone mass and an increased risk of fractures is an issue of major concern for physicians treating inflammatory bowel disease patients. Multiple causes for decreased bone mass have been identified in the past, but the role of inflammation may be of pivotal importance. We here discuss the latest insights into the pathogenesis of inflammatory bowel disease-related bone loss and the implications for treatment.

Publication types

  • Comment

MeSH terms

  • Humans
  • Inflammatory Bowel Diseases / complications*
  • Osteoporosis / etiology
  • Osteoporosis / immunology
  • Spinal Curvatures / etiology
  • Spinal Fractures / etiology*