Exposure assessment of French women and their newborn to brominated flame retardants: determination of tri- to deca- polybromodiphenylethers (PBDE) in maternal adipose tissue, serum, breast milk and cord serum

Environ Pollut. 2009 Jan;157(1):164-73. doi: 10.1016/j.envpol.2008.07.008. Epub 2008 Sep 19.


In the frame of a French monitoring program, tri- to deca- polybromodiphenylethers (PBDE) have been measured in maternal and cord serum, adipose tissue, and breast milk samples, collected from 93 volunteer women during caesarean deliveries. The seven major tri- to heptaBDE (BDE-28, 47, 99, 100, 153, 154, and 183) were detected in adipose tissue and breast milk with cumulated median values of 2.59 and 2.51 ng g(-1) l w. Nine highly brominated octa- to decaBDE (BDE-196, 197, 201, 202, 203, 206, 207, 208 and 209) was performed in the same samples, with cumulated median values of 2.73 and 3.39 ng g(-1) l w in adipose tissue and breast milk, respectively. At this opposite, median levels of octa- to decaBDE in maternal and cord serum appeared significantly higher than the levels of tri- to heptaBDE in the same matrices, i.e. 8.85 and 12.34 versus 0.98 and 0.69 ng g(-1) l w, respectively.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipose Tissue / chemistry*
  • Female
  • Fetal Blood / chemistry*
  • Flame Retardants / analysis*
  • Halogenated Diphenyl Ethers / analysis*
  • Halogenated Diphenyl Ethers / blood
  • Halogenated Diphenyl Ethers / chemistry
  • Humans
  • Infant, Newborn
  • Maternal Exposure
  • Milk, Human / chemistry*
  • Molecular Weight
  • Risk
  • Specimen Handling


  • Flame Retardants
  • Halogenated Diphenyl Ethers