Giant, congenital folliculosebaceous cystic hamartoma: a case against a pathogenetic relationship with trichofolliculoma

Am J Dermatopathol. 2008 Oct;30(5):500-3. doi: 10.1097/DAD.0b013e318183eb07.


Folliculosebaceous cystic hamartoma (FSCH) is a rare cutaneous hamartoma consisting of dilated folliculosebaceous units invested in mesenchymal elements. These solitary lesions typically affect adults, have a predilection for the central face or scalp, and remain less than 1.5 cm in greatest dimension. Although giant FSCH variants have been documented, the congenital presentation of a giant FSCH stands in contrast to earlier views of its histogenetic relationship with trichofolliculoma. We describe a giant pedunculated FSCH arising from the posterior neck of a 9-month-old Hispanic male and discuss various aspects of this highly unusual case.

Publication types

  • Case Reports

MeSH terms

  • Hair Follicle / pathology*
  • Hamartoma / diagnosis
  • Hamartoma / genetics*
  • Hamartoma / pathology*
  • Humans
  • Infant
  • Male
  • Mesoderm / pathology
  • Neck
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / genetics*
  • Skin Neoplasms / pathology*