[Postinfectious acute glomerulonephritis]

Nephrol Ther. 2009 Apr;5(2):97-101. doi: 10.1016/j.nephro.2008.06.001. Epub 2008 Sep 21.
[Article in French]

Abstract

Postinfectious acute glomerulonephritis mostly happens in children aged two to 10 years old. Typically, it follows group A beta-hemolytic streptococcus skin or upper respiratory tract infection. There is a latent period of one to three weeks before nephritic syndrome appears. Microscopic or macroscopic hematuria is always present. Proteinuria and decreased glomerular filtration rate are usually mild. By contrast, salt and water retention can be severe and complicated with hypertension, congestive heart failure or pulmonary edema. Fluid overload must be urgently treated by loop diuretics or renal replacement therapy in the most severe cases.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Antigens, Bacterial / immunology
  • Child
  • Child, Preschool
  • Complement Pathway, Alternative
  • Disease Progression
  • Edema / etiology
  • Edema / physiopathology
  • Glomerulonephritis / epidemiology
  • Glomerulonephritis / etiology*
  • Glomerulonephritis / therapy
  • Hematuria / etiology
  • Humans
  • Immune Complex Diseases / epidemiology
  • Immune Complex Diseases / etiology*
  • Immune Complex Diseases / therapy
  • Molecular Mimicry / immunology
  • Renal Replacement Therapy
  • Respiratory Tract Infections / complications*
  • Respiratory Tract Infections / immunology
  • Skin Diseases, Bacterial / complications
  • Skin Diseases, Bacterial / immunology
  • Sodium Potassium Chloride Symporter Inhibitors / therapeutic use
  • Streptococcal Infections / complications*
  • Streptococcal Infections / immunology
  • Streptococcus / immunology
  • Water-Electrolyte Imbalance / drug therapy
  • Water-Electrolyte Imbalance / etiology
  • Water-Electrolyte Imbalance / physiopathology

Substances

  • Antigens, Bacterial
  • Sodium Potassium Chloride Symporter Inhibitors