Tularemia in children

Indian J Pediatr. 2008 Nov;75(11):1129-32. doi: 10.1007/s12098-008-0180-9. Epub 2008 Sep 22.


Objective: Tularemia, an infection caused by the coccobacilus Francisella tularensis, can be a difficult disease process to diagnose and treat. The aim of this study was to evaluate an epidemic of tularemia in Bursa.

Methods: In this study, we included only pediatric cases. All the cases were diagnosed on clinical and serological grounds.

Results: During an epidemic of tularemia in a village of Bursa on December 2004, 70 people (60 adults, 10 children) fell ill. In children with tularemia, the oropharyngeal form predominated which was diagnosed 70% of cases. Most of the patients (80%) who had older than 10 years old, were treated with doxycycline. All patients recovered without complications.

Conclusion: The epidemic was thought to be waterborne. The vehicle of the infections was inadequately treated water which was used by the patient in the village.

MeSH terms

  • Adolescent
  • Adult
  • Animals
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use*
  • Child
  • Child, Preschool
  • Disease Outbreaks
  • Doxycycline / administration & dosage
  • Doxycycline / therapeutic use*
  • Female
  • Francisella tularensis / isolation & purification*
  • Humans
  • Male
  • Population Surveillance
  • Tularemia / diagnosis
  • Tularemia / drug therapy
  • Tularemia / epidemiology*
  • Tularemia / microbiology
  • Turkey / epidemiology
  • Water Microbiology
  • Water Supply


  • Anti-Bacterial Agents
  • Doxycycline