Hypoglycemic potential of Morus indica. L and Costus igneus. Nak.--a preliminary study

Indian J Exp Biol. 2008 Aug;46(8):614-6.

Abstract

Powdered leaves (500 mg/kg body weight) of medicinal plants M. indica and C. igneus known to possess therapeutic effect were supplemented to streptozotocin induced diabetic rats. Leaf powders of both the plants were able to reduce blood glucose levels in the animals by 38 and 21% respectively after 15 days of supplementation. The preliminary results suggest that both the plants possess potent hypoglycemic activity.

MeSH terms

  • Animals
  • Blood Glucose / metabolism
  • Body Weight / drug effects
  • Costus / chemistry*
  • Diabetes Mellitus, Experimental / chemically induced
  • Diabetes Mellitus, Experimental / drug therapy
  • Feeding Behavior / drug effects
  • Hypoglycemic Agents / therapeutic use*
  • Male
  • Morus / chemistry*
  • Rats
  • Rats, Wistar
  • Streptozocin / pharmacology
  • Water / metabolism

Substances

  • Blood Glucose
  • Hypoglycemic Agents
  • Water
  • Streptozocin