Of mice and men, and chandeliers

PLoS Biol. 2008 Sep 30;6(9):e243. doi: 10.1371/journal.pbio.0060243. Epub 2008 Sep 23.

Abstract

How does the human neocortex reliably propagate information through neural circuits? One mechanism appears to involve relying on strong connections from pyramidal neurons to interneurons and a depolarizing action of cortical chandelier cells.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Humans
  • Interneurons / cytology*
  • Interneurons / physiology
  • Interneurons / ultrastructure
  • Mice
  • Neocortex / cytology
  • gamma-Aminobutyric Acid

Substances

  • gamma-Aminobutyric Acid