Insights into mechanisms linking cardiac hypertrophy and atrial fibrosis: evidence for a role of histone deacetylase in atrial fibrillation pathophysiology and therapy

J Mol Cell Cardiol. 2008 Dec;45(6):707-8. doi: 10.1016/j.yjmcc.2008.09.001. Epub 2008 Sep 10.
No abstract available

Publication types

  • Comment
  • Editorial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Angiotensin II / genetics
  • Angiotensin II / metabolism
  • Animals
  • Atrial Fibrillation / chemically induced
  • Atrial Fibrillation / enzymology*
  • Atrial Fibrillation / genetics
  • Atrial Fibrillation / pathology
  • Cardiomegaly / congenital
  • Cardiomegaly / enzymology
  • Cardiomegaly / genetics
  • Cardiomegaly / pathology
  • Connexins / genetics
  • Connexins / metabolism
  • Enzyme Inhibitors / adverse effects*
  • Enzyme Inhibitors / pharmacology
  • Fibrosis
  • Gap Junction alpha-5 Protein
  • Histone Deacetylase Inhibitors*
  • Histone Deacetylases / metabolism*
  • Homeodomain Proteins / biosynthesis*
  • Homeodomain Proteins / genetics
  • Hydroxamic Acids / adverse effects*
  • Hydroxamic Acids / pharmacology
  • Mice
  • Mice, Transgenic
  • Time Factors

Substances

  • Connexins
  • Enzyme Inhibitors
  • Histone Deacetylase Inhibitors
  • Homeodomain Proteins
  • Hop protein, mouse
  • Hydroxamic Acids
  • Angiotensin II
  • trichostatin A
  • Histone Deacetylases