Virally associated arthritis 2008: clinical, epidemiologic, and pathophysiologic considerations

Arthritis Res Ther. 2008;10(5):215. doi: 10.1186/ar2480. Epub 2008 Sep 18.


Several viruses have been associated with the development of inflammatory arthritis, including the hepatitis viruses (hepatitis B virus and hepatitis C virus), HIV, the parvovirus B19, the human T-cell lymphotropic virus-I, and the alphaviruses. Here, we review the epidemiology, the pathophysiological mechanisms, the pertinent clinical and laboratory findings as well as the principles of therapy of the most common virus-associated arthritides. We believe that the knowledge of these key diagnostic and therapeutic features of virus-associated arthritides is important for the rheumatologist of the 21st century.

Publication types

  • Review

MeSH terms

  • Animals
  • Arthritis, Infectious / epidemiology*
  • Arthritis, Infectious / physiopathology*
  • Arthritis, Infectious / virology*
  • Humans
  • Virus Diseases / epidemiology*
  • Virus Diseases / physiopathology*