Serum nortriptyline levels in nursing mothers and their infants

Am J Psychiatry. 1991 Sep;148(9):1234-6. doi: 10.1176/ajp.148.9.1234.

Abstract

The nortriptyline levels of seven depressed mothers and their breast-fed infants were obtained. Nortriptyline was not detected in the infants' sera. However, two of four infants evaluated developed low concentrations of 10-hydroxynortriptyline. No adverse effects were observed.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Breast Feeding*
  • Depressive Disorder / blood*
  • Depressive Disorder / drug therapy
  • Humans
  • Infant*
  • Infant, Newborn / blood*
  • Nortriptyline / analogs & derivatives
  • Nortriptyline / blood*
  • Nortriptyline / therapeutic use
  • Puerperal Disorders / blood*
  • Puerperal Disorders / drug therapy

Substances

  • 10-hydroxynortriptyline
  • Nortriptyline