A new pathogenetically and functionally grounded way of large and giant ventral hernia repair is suggested. The anterior wall of rectus sheath is formed with own aponeurosis and the posterior wall is formed by the endoprothesis. It reduces the risk of the complications, typical for the subcutaneous mesh position and provides for elasticity of muscle-aponeurotic abdominal wall structures. Satisfactory early and follow-up results are achieved in all 34 patients treated using the method. No hernia recurrences were registered.