A special key for unlocking the door to targeted therapies of breast cancer

ScientificWorldJournal. 2008 Sep 21;8:905-8. doi: 10.1100/tsw.2008.110.

Abstract

Personalized medicine and targeted therapy is the best hope for patients with cancer. C-Met-HGF/SF inhibition may be an effective cancer treatment for ductal carcinoma of the breast as it is expected to be an important signalling target in a large number of malignancies.

MeSH terms

  • Breast Neoplasms / therapy*
  • Carcinoma, Intraductal, Noninfiltrating / therapy*
  • Hepatocyte Growth Factor / therapeutic use*
  • Humans
  • Proto-Oncogene Proteins c-met / drug effects*
  • Proto-Oncogene Proteins c-met / genetics
  • Receptor, ErbB-2 / metabolism*

Substances

  • Hepatocyte Growth Factor
  • Proto-Oncogene Proteins c-met
  • Receptor, ErbB-2