Description of the erythromycin-producing bacterium Arthrobacter sp. strain NRRL B-3381 as Aeromicrobium erythreum gen. nov., sp. nov

Int J Syst Bacteriol. 1991 Jul;41(3):363-8. doi: 10.1099/00207713-41-3-363.


Arthrobacter sp. strain NRRL B-3381T (T = type strain) is a nonmycelial, nonsporulating actinomycete that produces the macrolide antibiotic erythromycin. This bacterium differs in many ways from the type species of the genus Arthrobacter (Arthrobacter globiformis), suggesting that a taxonomic revision is appropriate. The G + C content of strain NRRL B-3381T DNA is 71 to 73 mol%, and the peptidoglycan of this organism contains LL-diaminopimelic acid. Evolutionary distance data obtained from 16S rRNA sequences identified NRRL B-3381T as the deepest branching member of the Nocardioides group of actinomycetes. The principal long-chain fatty acids which we identified that distinguished strain NRRL B-3381T from related G + C-rich bacteria were 10-methyloctadecanoic (tuberculosteric), octadecenoic, and hexadecanoic acids. These characteristics, together with phage typing and biochemical characteristics, form the basis for our recommendation that strain NRRL B-3381 should be the type strain of a new taxon, for which we propose the name Aeromicrobium erythreum.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Amino Acids / analysis
  • Arthrobacter / classification*
  • Arthrobacter / metabolism
  • Bacteria, Aerobic / classification*
  • Bacteria, Aerobic / metabolism
  • Base Composition
  • Base Sequence
  • Erythromycin / metabolism*
  • Fatty Acids / analysis
  • Gram-Positive Bacteria / classification*
  • Gram-Positive Bacteria / metabolism
  • Microscopy, Electron
  • Molecular Sequence Data
  • Peptidoglycan / chemistry
  • Phenotype
  • RNA, Ribosomal, 16S / genetics
  • Sequence Homology, Nucleic Acid
  • Soil Microbiology
  • Vitamin K / analysis


  • Amino Acids
  • Fatty Acids
  • Peptidoglycan
  • RNA, Ribosomal, 16S
  • Vitamin K
  • Erythromycin

Associated data

  • GENBANK/M37200
  • GENBANK/M37699