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Review
. 2008 Oct;66(10 Suppl 2):S182-94.
doi: 10.1111/j.1753-4887.2008.00104.x.

Vitamin D: A D-Lightful Health Perspective

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Review

Vitamin D: A D-Lightful Health Perspective

Michael F Holick. Nutr Rev. .

Abstract

Sunlight provides most humans with their vitamin D requirement. Adequate vitamin D(3) by synthesis in the skin or from dietary and supplemental sources is essential for bone health throughout life. Vitamin D deficiency is defined as a 25(OH)D concentration <20 ng/mL (50 nmol/L); vitamin D sufficiency as a 25(OH)D >30 ng/mL (75 nmol/L), and insufficiency as 21-29 ng/mL. Vitamin D deficiency and insufficiency has been linked to a wide variety of chronic diseases including common cancers, autoimmune, cardiovascular, and infectious diseases. Healthcare professionals need to be aware of the vitamin D deficiency pandemic. Guidelines for sensible sun exposure and supplemental vitamin D of 800-1000 IU/day are needed.

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