Condensin goes with the family but not with the flow

Genome Biol. 2008 Oct 6;9(10):236. doi: 10.1186/gb-2008-9-10-236.

Abstract

Condensin and cohesin are loaded onto yeast chromosomes by a common mechanism at RNA polymerase III transcribed genes. Whereas cohesin translocates from these loading sites to mediate cohesion at secondary locations, condensin remains, bringing distant sites together into clusters.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adenosine Triphosphatases / genetics
  • Adenosine Triphosphatases / metabolism*
  • Binding Sites
  • Cell Cycle Proteins / metabolism
  • Chromosomal Proteins, Non-Histone / metabolism
  • Chromosomes, Fungal
  • Cohesins
  • DNA-Binding Proteins / genetics
  • DNA-Binding Proteins / metabolism*
  • Models, Biological
  • Multiprotein Complexes / genetics
  • Multiprotein Complexes / metabolism*
  • RNA Polymerase III
  • Saccharomyces cerevisiae / metabolism

Substances

  • Cell Cycle Proteins
  • Chromosomal Proteins, Non-Histone
  • DNA-Binding Proteins
  • Multiprotein Complexes
  • condensin complexes
  • RNA Polymerase III
  • Adenosine Triphosphatases