Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. Mar-Apr 1991;54(2):66-9.

[Pikamilon Pharmacokinetics in Animals]

[Article in Russian]
  • PMID: 1884802

[Pikamilon Pharmacokinetics in Animals]

[Article in Russian]
B F Dorofeev et al. Farmakol Toksikol. .

Abstract

Pycamilon was shown to be rapidly absorbed in the blood (tmax = 0.23 h), to penetrate well through the blood-brain barrier and to be intensively uptaken by the animal organs and tissues and to be eliminated mainly in the urine (t1/2 = 0.51 h). The drug bioavailability at oral administration to mice is 21.9%, and to rats from 53 to 78.9% (according to the urinary excretion data).

Similar articles

See all similar articles

Publication types

Feedback