Imaging the infant retina with a hand-held spectral-domain optical coherence tomography device

Am J Ophthalmol. 2009 Feb;147(2):364-373.e2. doi: 10.1016/j.ajo.2008.08.010. Epub 2008 Oct 9.


Purpose: To evaluate and treat infant retina through the use of a hand-held spectral-domain optical coherence tomography (SD OCT) device in selected cases of Shaken Baby syndrome (SBS).

Design: Observational case series.

Methods: A novel SD OCT system was optimized and evaluated for infant imaging. An adult eye was imaged with both a standard clinical SD OCT system and the hand-held system. Four eyes of two infants with a history of SBS were imaged with the hand-held system. One infant was imaged again during follow-up examinations. Robust image processing algorithms were developed to create high-quality images. Images were assessed for usefulness in demonstrating pertinent morphologic features.

Results: The novel SD OCT unit proved effective for data acquisition and comparable with conventional chin-rest SD OCT. Rapid data acquisition limited motion artifact within the B-scan, although there was slight motion between B scans. The SD OCT images provided previously unseen details with regard to the morphologic features of retinal lesions in these infant eyes. This information influenced prognosis and management.

Conclusions: As with adults, the hand-held customized SD OCT proved to be an invaluable tool in the differentiation of disease processes or injury in these eyes under study. SD OCT imaging systems may be considered a useful adjunct to RetCam fundus photography for assessment and clinical management in cases of SBS.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Algorithms
  • Diagnostic Techniques, Ophthalmological / instrumentation*
  • Female
  • Fractures, Bone / diagnosis
  • Hematoma, Subdural / diagnosis
  • Humans
  • Infant
  • Magnetic Resonance Imaging
  • Male
  • Pilot Projects
  • Retina / pathology*
  • Retinal Hemorrhage / diagnosis*
  • Retinal Hemorrhage / surgery
  • Retinal Perforations / diagnosis*
  • Retinal Perforations / surgery
  • Shaken Baby Syndrome / diagnosis*
  • Shaken Baby Syndrome / surgery
  • Tomography, Optical Coherence / methods*