Impaired work performance among women with symptomatic uterine fibroids

J Occup Environ Med. 2008 Oct;50(10):1149-57. doi: 10.1097/JOM.0b013e3181895e10.


Objective: To assess the work impact of symptomatic uterine fibroids (UFs).

Methods: A cohort study compared 58 employed women with symptomatic UFs to 56 healthy controls. Data sources included a self-administered mail questionnaire and medical charts. At-work performance limitations and productivity loss were measured with the Work Limitations Questionnaire. Univariate and multivariate case-control group differences were tested.

Results: Based on adjusted mean scores, the UF group had significantly more at-work limitations and productivity loss than controls, while absence rates were similar. The UF group's performance was impaired 18% of the time on average versus 8% for controls (P-values, 0.005-0.040). At-work limitations were explained by depression symptoms, Non-White race/ethnicity, and poorer health-related quality of life.

Conclusions: Fibroids and related symptoms impose a burden on the working lives' of women, their employers, and the economy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Cohort Studies
  • Cost of Illness
  • Employment*
  • Female
  • Health Status
  • Humans
  • Leiomyoma / physiopathology*
  • Middle Aged
  • Surveys and Questionnaires
  • Task Performance and Analysis*
  • Young Adult