We report active tuberculosis in a pregnant physician caused by TB-transmission at the workplace. Because of increased liver enzymes, therapy with Rifampicin was temporarily interrupted. During pregnancy and the first seven month of the 12 month lactation period, the mother was treated for tuberculosis. The healthy newborn showed elevated GOT for the following two years after birth. Moderately elevated GPT was observed during the first months. A normal liver was seen in pre- and post-natal sonography. Therefore it is likely that the increased liver enzymes were caused by the chemotherapy of the mother.