Chiasmatic optic glioma

Neurochirurgia (Stuttg). 1991 May;34(3):90-3. doi: 10.1055/s-2008-1052062.


Optic nerve glioma is a rare tumor usually occurring in small children. How these tumors should be treated, is a matter of controversy. Recommended treatment ranges from a wait-and-see policy to radical excision with or without subsequent radio- or chemotherapy. Comparative data on these lesion are limited, as there are no randomized investigations and long-term studies reported in the literature. In 11 patients interstitial radiotherapy was carried out, by the implantation of J-125 seeds following confirmation of the histological diagnosis. The results are compared with those of 10 patients who underwent only biopsy for histological confirmation. CT-stereotactic biopsy to verify the diagnosis with subsequent interstitial irradiation is presented as an alternative therapy for optic gliomas.

MeSH terms

  • Adolescent
  • Adult
  • Astrocytoma / pathology
  • Astrocytoma / radiotherapy
  • Astrocytoma / surgery*
  • Biopsy
  • Brachytherapy / methods
  • Child
  • Child, Preschool
  • Combined Modality Therapy
  • Cranial Nerve Neoplasms / pathology
  • Cranial Nerve Neoplasms / radiotherapy
  • Cranial Nerve Neoplasms / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Iodine Radioisotopes / therapeutic use
  • Male
  • Optic Chiasm / pathology
  • Optic Chiasm / radiation effects
  • Optic Chiasm / surgery*


  • Iodine Radioisotopes