Kinetics of particle retention in the human respiratory tract

L Gradoń; A Podgórski

doi:10.1093/annhyg/35.3.249

Kinetics of particle retention in the human respiratory tract

Ann Occup Hyg. 1991 Jun;35(3):249-59. doi: 10.1093/annhyg/35.3.249.

Authors

L Gradoń¹, A Podgórski

Affiliation

¹ Institute of Chemical and Process Engineering, Warsaw University of Technology, Poland.

PMID: 1888098
DOI: 10.1093/annhyg/35.3.249

Abstract

A mathematical model of retention of insoluble aerosol particles penetrating the lungs during inhalation has been described. Based on data of the streams of deposited particles and their residence times in the subsequent generations of bronchial tree the retention dynamics of particles with diameters 5, 1 and 0.01 microns in the air-spaces has been determined.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Humans
Kinetics
Lung / metabolism*
Models, Biological*
Mucociliary Clearance / physiology*
Particle Size
Respiration / physiology*