Fluoxetine and norfluoxetine are potent inhibitors of P450IID6--the source of the sparteine/debrisoquine oxidation polymorphism

Br J Clin Pharmacol. 1991 Jul;32(1):136-7. doi: 10.1111/j.1365-2125.1991.tb05630.x.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Fluoxetine / analogs & derivatives*
  • Fluoxetine / pharmacology*
  • Humans
  • Imipramine / metabolism
  • Microsomes, Liver / drug effects*
  • Polymorphism, Genetic

Substances

  • Fluoxetine
  • norfluoxetine
  • Imipramine