A recognition tool for transient ischaemic attack

QJM. 2009 Jan;102(1):43-9. doi: 10.1093/qjmed/hcn139. Epub 2008 Oct 15.


Background: Scoring systems exist to assist rapid identification of acute stroke but not for the more challenging diagnosis of transient ischaemic attack (TIA).

Aim: To develop a clinical scoring system to assist with diagnosis of TIA.

Methods: We developed and validated a clinical scoring system for identification of TIA patients. Logistic regression analysis was employed.

Results: Our development cohort comprised 3216 patients. The scoring system included nine clinically useful predictive variables. After adjustment to reflect the greater seriousness of missing true TIA patients (a 2:1 cost ratio), 97% of TIA and 24% of non-TIA patients were accurately identified. Our results were confirmed during prospective validation.

Conclusion: This simple scoring system performs well and could be used to facilitate accurate detection of TIA.

MeSH terms

  • Age Factors
  • Aged
  • Algorithms*
  • Cohort Studies
  • Female
  • Humans
  • Ischemic Attack, Transient / diagnosis*
  • Ischemic Attack, Transient / physiopathology
  • Logistic Models
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Recurrence